Year 2021 (55)

Edition nr. 7-8

Corticosteroids for COVID-19

This article discusses the results of the published randomised studies into the effect of corticosteroids in hospitalised patients with COVID-19. The RECOVERY study found a reduction of mortality among patients using dexamethasone, especially pat ...

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Antidotes for direct oral anticoagulants

Several years after the introduction of the direct oral anticoagulants (DOACs), two specific antidotes were authorised. Idarucizumab reverses the action of the direct thrombin inhibitor dabigatran, and andexanet alfa reduces the action of the fac ...

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Colchicine for coronary heart disease

Is it advisable to prescribe a low dose of colchicine (0.5 mg a day) as part of the secondary prevention of coronary heart disease? Several studies have assessed the efficacy of colchicine for this indication, and some meta-analyses have recently ...

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Neutralising monoclonal antibodies for COVID-19

A number of monoclonal antibodies have been developed for use in patients infected with SARS-CoV-2. Clinical research has shown that these monoclonal antibodies inhibit viral replication in recently infected non-hospitalised patients to a limited ...

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