Year 2020 (54)

Edition nr. 11-12

Ballerine® copper IUD

Frans M. Helmerhorst, Peter H.Th.J. Slee, Marielle A.E. Nieuwhof
Nr 11-12|2020 (54)|Page 123-127|New|doi: 10.35351/gebu.2020.11-12.21|14-01-2021

The ‘intrauterine ball’ Ballerine®, a intrauterine contraceptive device (IUD) made up of copper beads (copper surface area 300 mm2) has no proven added value over copper IUDs of first choice, such as T-shaped and horseshoe-shaped copper IUDs (wit ...

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Drug contamination

Leo M.L. Stolk
Nr 11-12|2020 (54)|Page 121-122|New|doi: 10.35351/gebu.2020.11-12.20|22-12-2020

The media have recently reported several cases of so-called contaminated drugs. The problem concerns contamination with impurities that had arisen in the production of the active ingredient. These impurities were the result of changes in the prod ...

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Umbrella reviews of drugs

Leo M.L. Stolk
Nr 11-12|2020 (54)|Page 117-120|New|doi: 10.35351/gebu.2020.11-12.19|21-12-2020

The number of published systematic reviews of randomised drug trials has risen rapidly in recent years. This has led to the development of ‘overviews’ of systematic reviews, known as ‘umbrella reviews’. These umbrella reviews are similar to syste ...

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