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Level of evidence: randomised or observational studies?

Randomised controlled trials (RCT’s) are regarded as the gold standard in medical research to prove whether presumed effects of medicinal or other treatments are of a causal nature. There may however be financial, practical or ethical issues whic ...

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Clinical relevance of research findings

Doctors, pharmacists and other care providers cannot always easily tell whether the findings of research into drugs and medical devices, often presented attractive and ‘glossy’ ways, will actually benefit their patients in their everyday practice ...

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