Effect of acetylsalicylic acid in early secondary prevention after TIA or cerebral infarction

The findings of this study indicate that the protective effect of acetylsalicylic acid in the secondary prevention of atherothrombotic complications after a stroke is highest in the early stages and that its protective effect in the longer term has been overestimated. The opposite is true for dipyridamol. This implies that immediate use of acetylsalicylic acid when early symptoms suggestive of stroke appear might be recommended. If a GP is called in immediately, he or she could prescribe this drug regardless of the further management. The use of acetylsalicylic acid is no contraindication for thrombolysis or thrombectomy. The potential risk of using acetylsalicylic acid before a cerebral haemorrhage has been excluded (that is, before a brain scan has been made) is low.

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*The literature refers to the Dutch text