The Geneesmiddelenbulletin Foundation consists of a board of governors, an editorial team, an editorial board and a scientific advisory council, each with their own part to play. The board of governors has a purely facilitating role, and principally concerns itself with financial, organisational and personnel matters. It has no influence on the content of the editorial processes within Ge-Bu.

The editor-in-chief is responsible for the content of the journal, and leads the editorial team (consisting of the editors, editorial manager, office manager and external staff). The editor-in-chief has complete editorial freedom in determining the content and publication of Ge-Bu articles. The members of the editorial board (RC) review the manuscripts and advise the editor-in-chief and the editorial team on the suitability of a manuscript for publication. The editorial board consists of a minimum of five members, including general practitioners, pharmacists (both hospital- and community-based) and medical specialists. They are members in a private capacity and do not represent any organisations. They meet on a monthly basis.

The scientific advisory council (WAR) offers solicited and unsolicited advice to the board of governors, the editor-in-chief, the editorial team and the editorial board regarding policy matters in general and content-related matters in particular, including proposals for suitable topics for publication in Ge-Bu. Members of the council are also invited, sometimes in a personal capacity only, to comment on manuscripts. The council meets twice a year and consists of a minimum of 10 and a maximum of 20 persons, including prescribing specialists, pharmacists (both hospital- and community-based), general practitioners and methodologists. They too are members in a private capacity and do not represent any organisations.