Recent articles
Amoxicillin is the drug of first choice to treat community-acquired pneumonia (CAP) in children below 5 years of age. There is, however, no consensus about the dosage or the duration of the course ...
Update: does HPV vaccination prevent cervical carcinoma?
A previous Ge-Bu article concluded that too little research had been published to answer the question whether vaccination against human papillomavirus (HPV) protects against cervical carcinoma. De ...
Vaccines for COVID-19: an update
Since the beginning of 2021, two mRNA vaccines and two vector vaccines against SARS-CoV-2 have been available in the Netherlands, and a large proportion of the population have now been vaccinated. ...
Esketamine for severe depression
A recently published Cochrane systematic review and meta-analysis examined the efficacy and adverse effects of esketamine (and other drugs) to treat severe (or very severe) depression. Treatment o ...
Finerenone for type 2 diabetes and chronic kidney disease
Treatment for patients with type 2 diabetes mellitus and chronic kidney or cardiovascular disease has to focus on blocking the renin-angiotensin-aldosterone system (RAAS). In specific cases, the ( ...
Ondansetron for children with gastro-enteritis
Ondansetron is a serotonin receptor antagonist which has been authorised for use as an anti-emetic in the context of chemotherapy (from an age of 6 months) and radiotherapy (in adults). It has als ...
Direct-acting antiviral agents for chronic hepatitis C
Recent years have seen major progress in the treatment of chronic hepatitis C. New direct-acting antiviral agents (DAAs) have become available in the Netherlands from the end of 2014. Combinations ...
New drugs for migraine prophylaxis
The discovery of the role of ‘calcitonin gene-related peptide’ (CGRP) in the development of migraine enabled new drugs for the treatment of this condition to be developed. The monoclonal CGRP anta ...