Recent articles

The new coronavirus (SARS-CoV-2) is raising many questions among care providers, including questions about the use of drugs that could have a negative influence on the course of the COVID-19  dise ...

Research findings published in 2019 lend support to the view that the risk of hormone therapy for menopausal symptoms in women might be underestimated. There has been ongoing debate for years abou ...

Clopidogrel, which is used as a platelet aggregation inhibitor for the prophylaxis of atherothrombotic complications, is enzymatically activated by the enzyme CYP2C19. Patients whose genetic predi ...

Cytochrome P450 enzymes (CYP enzymes) are involved in the metabolism of many drugs. Since the activity of CYP enzymes can be inhibited or stimulated by other drugs, a large variety of interactions ...

Randomised controlled trials (RCT’s) are regarded as the gold standard in medical research to prove whether presumed effects of medicinal or other treatments are of a causal nature. There may howe ...

In view of the vital role played by the liver in drug metabolism, it is surprising how often this proceeds without any damage. Nevertheless it is clinically relevant for doctors and pharmacists to ...

Despite evidence of its lack of effectiveness, the antidepressant mirtazapine is being used as a treatment option for insomnia, as has previously been discussed in Ge-Bu. Insofar as they have been ...

It is well-known that technicians employed by commercial companies are involved in the maintenance of working on medical devices in hospitals. Unclear, however, is what exactly they do, what their ...