Recent articles

Clopidogrel, which is used as a platelet aggregation inhibitor for the prophylaxis of atherothrombotic complications, is enzymatically activated by the enzyme CYP2C19. Patients whose genetic predi ...

Cytochrome P450 enzymes (CYP enzymes) are involved in the metabolism of many drugs. Since the activity of CYP enzymes can be inhibited or stimulated by other drugs, a large variety of interactions ...

Randomised controlled trials (RCT’s) are regarded as the gold standard in medical research to prove whether presumed effects of medicinal or other treatments are of a causal nature. There may howe ...

In view of the vital role played by the liver in drug metabolism, it is surprising how often this proceeds without any damage. Nevertheless it is clinically relevant for doctors and pharmacists to ...

Despite evidence of its lack of effectiveness, the antidepressant mirtazapine is being used as a treatment option for insomnia, as has previously been discussed in Ge-Bu. Insofar as they have been ...

It is well-known that technicians employed by commercial companies are involved in the maintenance of working on medical devices in hospitals. Unclear, however, is what exactly they do, what their ...

There is currently a trend to start the treatment of children with type 1 diabetes mellitus with a subcutaneous insulin pump, rather than with the conventional insulin injections. No clear evidenc ...

Calcipotriol/betamethasone aerosol foam 0.05mg/g and 0.5 mg/g (Enstilar®) were registered in 2016 for the ‘local treatment of psoriasis vulgaris in adults’. The combination of calcipotriol and bet ...