Moxifloxacine (Avelox®), antimicrobieel middel

1. Productinformatie Avelox via:, Geneesmiddeleninformatiebank. Additionele informatie kan worden gevonden op:, 1024, index.asp. 
2. Wilson R, et al. Five day moxifloxacin therapy compared with 7 day clarithromycin therapy for the treatment of acute exacerbations of chronic bronchitis. J Antimicrob Chemother 1999; 44: 501-513.
3. Chodosh S, et al. Short-course moxifloxacin therapy for treatment of acute bacterial exacerbations of chronic bronchitis. Respir Med 2000; 94: 18-27.
4. deAbate CA, et al. The safety and efficacy of short course (5-day) moxifloxacin vs. azithromycin in the treatment of patients with acute exacerbation of chronic bronchitis. Respir Med 2000; 94: 1029-1037.
5. Schaberg T, et al. A multinational, multicentre, non-blinded, randomized study of moxifloxacin oral tablets compared with co-amoxiclav oral tablets in the treatment of acute exacerbation of chronic bronchitis. J Int Med Res 2001; 29: 314-328.
6. Hoeffken G, et al. The efficacy and safety of two oral moxifloxacin regimens compared to oral claritromycin in the treatment of community-acquired pneumonia. Respir Med 2001; 95: 553-564.
7. Petitpretz P, et al. Oral moxifloxacin vs high-dose amoxicillin in the treatment of mild-to-moderate, community-acquired, suspected pneumococcal pneumonia in adults. Chest 2001; 119: 185-195.
8. Finch R, et al. Randomized controlled trial of sequential intravenous and oral moxifloxacine compared with sequential i.v. and oral co-amoxiclav with or without claritromycin in patients with community-acquired pneumonia requiring initial parenteral treatment. Antimicr Ag Chemother 2002; 46: 1746-1754.
9. Siegert R, et al. A comparison of the safety and efficacy of moxifloxacin (BAY 12-8039) and cefuroxime axetil in the treatment of acute bacterial sinusitis in adults. Respir Med 2000; 94: 337-344.
10. Burke T, et al. Comparison of moxifloxacin and cefuroxim axetil in the treatment of acute maxillary sinusitis. Clin Ther 1999; 21: 1664-1677.
11. Rakkar S, et al. Moxifloxacin versus amoxicillin clavulanate in the treatment of acute maxillary sinusitis: a primary care experience. Int J Clin Pract 2001; 55: 309-315.
12. Ball P. Quinolone-induced QT interval prolongation: a not-so-unexpected class effect. J Antimicrob Chemother 2000; 45: 557-559.
13. Frothingham R. Rates of torsades de pointes associated with ciprofloxacin, ofloxacin, levofloxacin, gatifloxacin, and moxifloxacin. Pharmacother 2001; 21: 1468-1472.
14. Rubinstein E, et al. Cardiotoxity of fluoroquinolones. J Antimicrob Chemother 2002; 49: 593-596.
15. Dukes MNG, et al. Meyler's side effects of drugs (14e ed.). Amsterdam: Elsevier, 2000.


  • dr J.J. Tukker