Gammahydroxyboterzuur (Xyrem®), behandeling kataplexie

1. IB-tekst gammahydroxyboterzuur (Xyrem®) via:, Geneesmiddeleninformatiebank. 
2. Vignatelli L, et al. Antidepressant drugs for narcolepsy. Cochrane Database Syst Rev 2005; 3: CD003724. 
3. The US Xyrem Multicenter Study Group. A randomized, double blind, placebo-controlled multicenter trial comparing the effects of three doses of orally administered sodium oxybate with placebo for the treatment of narcolepsy. Sleep 2002; 25: 42-49. 
4. Xyrem International Study Group. Further evidence supporting the use of sodium oxybate for the treatment of cataplexy: a double-blind, placebo-controlled study in 228 patients. Sleep Med 2005; 6: 415-421. 
5. Scrima L, et al. The effects of g-hydroxybutyrate on the sleep of narcolepsy patients: a double blind study. Sleep 1990; 13: 479-480. 
6. Lammers GJ, et al. Gamma hydroxybutyrate and narcolepsy: a double-blind placebo-controlled study. Sleep 1993; 16: 216-220.  


  • dr D. Bijl